The Laboratory for Custom Synthesis and Lead Development is supported by four MIDD members, which are faculty members of the Department of Chemistry and Biochemistry. Each investigator supports the Laboratory with a distinctive synthesis expertise and laboratory setup.
Dr. Peng’s expertise in organic synthesis includes nucleic acid and nucleotide chemistry. Improved synthesis routes have been developed to generate these complex molecules with functional groups to enable click-chemistry and . The group has also great knowledge to . Transition metal-catalyzed and are performed frequently in the laboratories of Dr. Hossain. Outstanding methods to have been developed and can be performed with excellent stereocontrol. The laboratory of Dr. Cook support of biological active compounds and the synthesis of usually produced with many synthetic steps and several stereochemistry centers. Dr. Arnold’s expertise is the that enable lead compound optimization using specialized laboratory equipment. The group is also supporting the synthesis of drug metabolites.