Digging deeper into the surface - Investigating subsurface oxygen and its reactivity in silver using lattice-gas models, DFT, and Monte Carlo simulations First-row atoms, such as hydrogen, carbon, and oxygen, not only adsorb on the surface of a solid but …
Chemical Tools for DNA-Protein Cross-Link Formation and Study DNA-protein cross-links (DPCs) are highly toxic lesions formed via a variety of chemical pathways and as intermediates in enzyme transformations. DPCs are potent blocks of helicases, as well as DNA and RNA …
Sometimes DNA Damage is Only the Beginning DNA damage is detrimental to genome integrity and can be mutagenic and/or cytotoxic. The latter lie at the etiology of disease but is also the goal of many anti-cancer therapeutics. Consequently, understanding this …