{"id":82623,"date":"2020-04-16T09:33:11","date_gmt":"2020-04-16T14:33:11","guid":{"rendered":"https:\/\/uwm.edu\/news\/?p=82623"},"modified":"2020-04-16T09:33:11","modified_gmt":"2020-04-16T14:33:11","slug":"landmark-study-of-adolescent-brain-development-renews-for-seven-years-2","status":"publish","type":"post","link":"https:\/\/uwm.edu\/news\/landmark-study-of-adolescent-brain-development-renews-for-seven-years-2\/","title":{"rendered":"Landmark study of adolescent brain development renews for seven years"},"content":{"rendered":"

The National Institutes of Health has awarded nearly $290 million of new funding to research institutions around the country, including the University of Wisconsin-Milwaukee, to continue the Adolescent Brain Cognitive Development (ABCD) Study. The funding extends the project, the largest long-term study of brain development and child health ever conducted in the United States, for seven more years.<\/p>\n

Launched in 2015, ABCD\u00a0is following 11,750 children \u2013 386 of them from southeastern Wisconsin \u2013 for at least 10 years, starting at ages 9 to 10. The\u00a0aim is to generate detailed data about how young brains mature.<\/p>\n

For the last three years, the\u00a051ÁÔÆæ site’s<\/a>\u00a0researchers have been documenting how variables such as exposures to drugs (including nicotine, alcohol, and marijuana), screen time activities, sleep patterns,\u00a0physical activity and family relationships interplay to predict emotional, cognitive and brain development throughout the adolescent years.<\/p>\n

The young participants undergo interviews and behavioral assessments once or twice a year, with physiological measures of cardiovascular health and neuroimaging of brain structure and function every two years, said Krista Lisdahl, 51ÁÔÆæ associate professor of psychology who leads the 51ÁÔÆæ scientific team.<\/p>\n

\u201cWe\u2019ve already begun collecting information on multiple factors that influence early substance use, like alcohol use and vaping, and onset and severity of mental health problems and trauma outcomes among tweens,\u201d said Lisdahl. \u201cWe also want to know how disruptions from the COVID-19 pandemic might impact families, given new stresses such as unemployment, illness, and separation from friends and family.\u201d<\/p>\n

Lisdahl and students in the\u00a0Brain Imaging and Neuropsychology (BraIN) Laboratory at 51ÁÔÆæ<\/a>\u00a0also have played a leading role in several ABCD sub-studies. One examines\u00a0how levels of endocannabinoids\u00a0impact emotional and brain development.\u00a0Endocannabinoids are natural chemicals in the brain that marijuana interacts with. These brain chemicals also\u00a0regulate many processes in the body, such as immune response, stress response, memory, and appetite and metabolism.<\/p>\n

Another sub-study Lisdahl is involved with\u00a0examines the impact of\u00a0local drug (alcohol, marijuana, nicotine and opiate) policies and early teenage substance use.<\/p>\n

In addition to Lisdahl, the\u00a051ÁÔÆæ scientific team includes Christine Larson, professor of psychology; Paul Florsheim, professor of public health; and\u00a0more than\u00a025 students in the BraIN Laboratory. Consultants include Drs. Andrew Nencka, Cecilia Hillard and Lisa Conant at the Medical College of Wisconsin, and Dr. Staci Gruber at Harvard Medical School.<\/p>\n

The nationwide ABCD study has already produced two sets of high-quality baseline data for the broader research community through the\u00a0National Institute of Mental Health Data Archive<\/a>\u00a0to enable both ABCD investigators and non-ABCD researchers to pursue their own research questions. The data \u2014 so far more than 140 terabytes’ worth \u2014 include basic participant demographics, assessments of physical and mental health, substance use, culture and environment, and neurocognition, tabulated structural and functional neuroimaging data, and minimally processed brain images.<\/p>\n

The comprehensive dataset, which is broken down by sex, racial\/ethnic group, and socioeconomic status, allows researchers to address numerous questions that may ultimately inform health decisions and policies related to education, nutrition, physical activity, sleep, and prevention of substance use and mental illness.<\/p>\n

\u201cSince the participants are now in their vulnerable middle school years or are beginning high school, this is a critical time to learn more about what enhances or disrupts a young person\u2019s life trajectory,\u201d said Dr. Nora D. Volkow, director of the National Institute on Drug Abuse.<\/p>\n

Information about the\u00a0ABCD Study<\/a>\u00a0and the\u00a0study sites<\/a>\u00a0can be found online.<\/p>\n","protected":false},"excerpt":{"rendered":"

The National Institutes of Health has awarded nearly $290 million of new funding to research institutions around the country, including 51ÁÔÆæ, to continue the Adolescent Brain Cognitive Development (ABCD) Study.<\/p>\n","protected":false},"author":836,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","uwm_wg_additional_authors":[]},"categories":[174,200],"tags":[],"section":[138,135],"display_categories":[],"related-coverage":[],"uwmnews-feed":[158,161],"class_list":["post-82623","post","type-post","status-publish","format-standard","hentry","category-news","category-news-in-brief","section-childrens-health","section-health","uwmnews-feed-letters-science","uwmnews-feed-hard-science"],"yoast_head":"\nLandmark study of adolescent brain development renews for seven years<\/title>\n<meta name=\"description\" content=\"The National Institutes of Health has awarded nearly $290 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