{"id":71133,"date":"2019-05-08T09:44:47","date_gmt":"2019-05-08T14:44:47","guid":{"rendered":"https:\/\/uwm.edu\/news\/?p=71133"},"modified":"2019-05-13T18:10:29","modified_gmt":"2019-05-13T23:10:29","slug":"uwm-senior-honored-for-undergraduate-research","status":"publish","type":"post","link":"https:\/\/uwm.edu\/news\/uwm-senior-honored-for-undergraduate-research\/","title":{"rendered":"51ÁÔÆæ senior honored for undergraduate research"},"content":{"rendered":"

Sarah Philippi was honored last week by the national Council of Undergraduate Research as one of just 60 students from around the country chosen to present their research work at Posters on the Hill in Washington, D.C.\u00a0She is only the second student ever from 51ÁÔÆæ selected for this honor, and the second in two years. Math and physics major Kirill Shmilovich was chosen last year<\/a>.<\/p>\n

She attended a reception and had the opportunity to visit Wisconsin congressional members and staff to discuss the importance of federal funding for research.<\/p>\n

Philippi has been working with Karyn Frick<\/a>, professor of psychology, since the second semester of her first year at 51ÁÔÆæ. Their work focuses on the neurobiology of learning and memory.<\/p>\n

\u201cThis is a tremendous honor because Sarah was the only one in Wisconsin selected,\u201d Frick said. \u201cThe fact that she was able to go and represent not only our lab, but also 51ÁÔÆæ, is fantastic because it showcases the quality of undergraduate research at 51ÁÔÆæ. It\u2019s a great opportunity for the university to shine.\u201d<\/p>\n

\"Three
While in Washington, Philippi visited several congressional offices, including that of Sen. Tammy Baldwin. With her are Nigel Rothfels, director of 51ÁÔÆæ\u2019s Office of Undergraduate Research, and Baldwin staffer Megan May.<\/figcaption><\/figure>\n

In addition to her selection for Posters on the Hill, Philippi was one of seven 51ÁÔÆæ Senior Excellence in Research Award winners for 2018-2019 and was admitted to five of the top neuroscience PhD programs throughout the country, according to Frick.<\/p>\n

Philippi has decided to continue her research on Alzheimer\u2019s disease in the doctoral program at the Icahn School of Medicine at Mount Sinai in New York City.<\/p>\n

Over the past year, she\u2019s been studying the how sex, the potent hormone 17\u03b2-estradiol and the genetic risk factor APOE4 interact to influence the incidence and severity of Alzheimer\u2019s disease, using mice specially bred to exhibit Alzheimer\u2019s pathology. The mice are tested on a variety of behavioral tasks to examine these interactions.<\/p>\n

The work involves\u00a0two genetic variants of the lipid-carrying protein Apolipoprotein E termed APOE3 and APOE4, the latter of which is the leading genetic risk\u00a0factor for developing the most common form of Alzheimer\u2019s. Women who carry the APOE4 variant are at far greater risk of developing Alzheimer\u2019s disease than men, and are less responsive to the beneficial effects of estrogen therapy. Philippi\u2019s work is designed to figure out why. The results of this project will provide sorely needed information regarding the causes of Alzheimer\u2019s, a disease that disproportionately affects women in general, Philippi said.<\/p>\n

At Mt. Sinai, Philippi will be a graduate student in the neuroscience program, rotating through a number of labs in her first year to broaden her understanding of Alzheimer\u2019s, she said.<\/p>\n

\u201cWe want to eventually transfer the knowledge to humans,\u201d she said, helping other researchers get a better understanding of how hormones regulate memory consolidation.<\/p>\n

Philippi\u2019s\u00a0interest in the topic grew out a first-year course on the physiology of psychology. When Philippi expressed her interest in finding out more about this area at the cellular level, her teaching assistant, Lisa Taxier, who worked in Frick\u2019s lab, suggested that Philippi apply.<\/p>\n

\u201cI liked the idea of studying learning and memory and the role of hormones. It has been a really empowering experience to explore these topics firsthand as well as contribute to these research initiatives.\u201d<\/p>\n

Proud to represent 51ÁÔÆæ<\/h3>\n

Philippi said she was proud to represent 51ÁÔÆæ and the value and importance of research to members of the congressional delegation.<\/p>\n

\u201cI\u2019ve been saying for a really long time that increasing awareness about undergraduate research is one of the most important things to me, she said. \u201cIf I hadn\u2019t stumbled across it, I would never have known that this is what I wanted to do as a career.\u201d<\/p>\n

Nigel Rothfels, director of the Office of Undergraduate Research, and Tom Luljak, vice chancellor of University Relations, accompanied Philippi to the D.C. events.<\/p>\n

51ÁÔÆæ is nationally recognized for its undergraduate research. In November, the Council on Undergraduate Research\u00a0awarded the 2018 Campus-Wide Award for Undergraduate Research Accomplishments<\/a>\u00a0to the university in recognition of the quality and depth of the research opportunities it provides to its undergrad students. 51ÁÔÆæ was one of two institutions nationally to receive the award, which was presented in January.<\/p>\n","protected":false},"excerpt":{"rendered":"

Sarah Philippi was one of just 60 students from around the country chosen to present their research work at Posters on the Hill in Washington, D.C. 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