51ÁÔÆæ

Elizabeth Liedhegner

  • Member, Milwaukee Institute for Drug Discovery (MIDD)

Assistant Professor of Biomedical Science

Education

Ph DÌýPharmacology, ÌýCase Western Reserve UniversityÌý2010.

BSÌýBiochemistry, ÌýSpring Hill CollegeÌý2004.

Interest & Expertise

Dr. Elizabeth Liedhegner is a Team Scientist in the department of Biomedical Sciences at the University of Wisconsin Milwaukee, engaged in understanding cellular signaling pathways in disease processes. She obtained her PhD in 2011 from Case Western Reserve University focusing the utilization of a neuronal cell model to study the oxidative stress and cell signaling pathways induced by the utilization of Levodopa therapy to treat Parkinson's Disease. Dr. Liedhegner conducted her postdoctoral studies at the Medical College of Wisconsin where she utilized mammalian models to study endocannabinoid trafficking mechanism alterations related to post-traumatic stress disorder.

Dr. Liedhegner's current research programs are focused on exploring cellular signaling mechanisms, including oxidative changes, that impact protein function and cellular health in various altered states, such as disease and trauma. The overall goal of this research is to define cellular mechanisms in culture systems and animal models that are important to disease and disorder development and progression. For this research, she employs a variety of techniques to assay whole cells including live cell imaging and immunofluorescent staining techniques, examination of signaling changes through reporter assays, and protein modifications that result in altered cellular signaling

Selected Publications

Liedhegner, E. S., Bojar, B., Beattie, R., Cahak, C., Hristova, K., & Skwor, T. (2022, February).ÌýÌýAntibiotics/MDPI,Ìý11(2), 260-278.
Liedhegner, E. S., Sasman, A., & Hillard, C. J. (2014).ÌýÌýJournal of Neurochemistry,Ìý128(4), 491-506.
Liedhegner, E. S., Vogt, C. D., Sem, D. S., Cunningham, C. W., & Hillard, C. J. (2014).ÌýÌýMolecular Neurobiology,Ìý50(1), 149-158.
Sabens Liedhegner, E. A., Gao, X. H., & Mieyal, J. J. (2012).ÌýÌýAntioxidants and Redox Signaling,Ìý16(6), 543-566.
Sabens Liedhegner, E. A., Stellar, K. M., & Mieyal, J. J. (2011).ÌýÌýJournal of Chemical Research and Toxicology,Ìý24(10), 1644-1652.
Sabens, E. A., Distler, A. M., & Mieyal, J. J. (2010).ÌýÌýBiochemistry,Ìý49(12), 2715-2724.
Sabens, E. A., & Mieyal, J. J. (2009).ÌýÌýMassala, Mazza, G., & Hoboken, G. (Eds.).ÌýGlutathione and Sulfer Amino Acids in Human Health and Disease, 121-156.
Mieyal, J. J., Gallogly, M. M., Qanungo, S., Sabens, E. A., & Shelton, M. D. (2008).ÌýÌýAntioxid Redox Signal,Ìý10(11), 1941-1988.
Offer, T., Ames, B. N., Bailey, S. W., Sabens, E. A., Nozawa, M., & Ayling, J. E. (2007).ÌýÌýThe FASEB Journal,Ìý21(9), 2101-2107.

Honors & Awards

Dean's Award for Outstanding ServiceÌý(2021, May 7)Ìý51ÁÔÆæ College of Health Sciences.

International Cannabinoid Research Symposium travel awardÌý(2012)ÌýNational Institutes of Health (NIH).

International Cannabinoid Research Symposium travel awardÌý(2011)ÌýNational Institutes of Health (NIH).
Postdoctoral poster presentation winnerÌý(2011)ÌýMilwaukee Chapter Society of Neuroscience.
3rd place poster presentationÌý(2010)ÌýResearch ShowCASE.
Gordon Research Conference Travel AwardÌý(2010)ÌýNational Science Foundation.
Biomedical Graduate Student Symposium poster presentation winnerÌý(2009)Ìý.
Predoctoral Fellowship: NIH Institutional Metabolism Training Grant (T32 DK007319)Ìý(2009)ÌýNational Institutes of Health (NIH).
Greenfield Travel Award: Best journal club presentationÌý(2006)ÌýCWRU Department of Pharmacology.
Predoctoral Fellowship: NIH Institutional Molecular Training Grant (T32 GM008803)Ìý(2005)ÌýNational Institutes of Health (NIH).