The MIDD has been collaborating with Glen Hills Middle School teacher Lalitha Murali and her students supported by the iEDU program Cubes in Space. This program is for non-university students to conduct suborbital scientific and engineering research. The purpose of …
Nearly 1/3 of Americans will experience an anxiety disorder in their lifetime resulting in impaired social function and reduction of quality of life. Unfortunately, existing anxiety medications suffer from delayed or inadequate efficacy and sedative-hypnotic effects. Development of additional anxiolytics …
Glioblastoma (GBM) is an extremely aggressive cancer for which there are limited treatment options. Despite recent advances in therapy, the prognosis remains dismal and patient survival is short. After standard therapy, the recurrent tumors become resistant to therapy and render …
The effects of space travel on the human body, particularly on the skeletal system, are a critical area of research especially considering NASA鈥檚 goals to send humans to the moon again and to Mars (Artemis Accords). As astronauts venture beyond …
Protein-protein interactions (PPI) stand at the heart of numerous metabolic pathways and signaling networks, intricately linked to various diseases, marking them as prime targets for therapeutic intervention. Despite their significance, these interaction have eluded drug discovery due to their complexity …
Living systems are affected by exposure to gravity, thus, changing gravity influences biological life and processes. Currently, the effect of microgravity on breast cancer development, e.g. inhibition or progression, is not fully understood. Prof. Cheng’s research is focused on the …
Globally, over 70% of freshwater is used for agriculture to produce crops, which provide 30-40% of the world’s gross food output. It is inevitable to seek alternative sources of water, such as recycled water and agricultural return flows, to guarantee …
Glioblastoma (GBM) is the most aggressive of all brain tumors with limited treatment options and no cure. Even after multimodal treatments by surgical resection of tumor, chemo and radiotherapy, the prognosis is poor (median survival <15 months) and recurrence is …
This 4th research grant won by Function Therapeutics, valued at up to $413,908, is titled 鈥淚nhibitors of Thromboinflammation for Acute Kidney Injury鈥�. Function and the lab of Dr. Chris Dockendorff have collaborated with the MIDD for around 10 years. More recently, …
Cytokines are very important inflammatory signaling molecules that have been intensively studied since their identification in 1957. Crystal structures and recently electron microscopy structures of cytokines in complex with their receptors have been reported but their quaternary structures involving several …