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CREATED:20241029T190037Z
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UID:10001358-1730476800-1730480400@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Ethan Degner
DESCRIPTION:Dr. Ethan Degner of Wisconsin Lutheran College will present a talk about his work entitled\, “Chronicling a mosquito’s sex life from intromission to oviposition.” \nThe abstract is as follows: \n“Each year\, mosquito-borne infections kill hundreds of thousands and sicken hundreds of millions more. Controlling populations of mosquitoes is a public health imperative\, but despite decades of effort and technological advances\, mosquitoes remain humanity’s number one killer.  \nManipulating mosquito reproduction offers a promising avenue by which mosquito populations may be controlled\, but doing so requires an intimate understanding of mosquito reproduction\, from mating to egg-laying and a host of events in between. In this seminar\, I use the yellow fever mosquito Aedes aegypti to chronicle a mosquito’s reproductive life\, highlighting the modifications that a mosquito’s sperm undergo prior to fertilization. I also present efforts to catalog the proteins and transcripts involved in these events. Proper sperm function within a female is a requirement for producing the next generation of pathogen-transmitting mosquitoes\, and therefore understanding the molecular and cellular underpinnings that govern mosquito reproduction may allow new methods for mosquito control.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:/biology/event/biological-sciences-colloquium-dr-ethan-degner/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:/biology/wp-content/uploads/sites/21/2024/10/2024-Nov-01-Degner.jpg
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241107T170000
DTEND;TZID=America/Chicago:20241107T190000
DTSTAMP:20260419T223725
CREATED:20241104T200827Z
LAST-MODIFIED:20241104T201447Z
UID:10001359-1730998800-1731006000@uwm.edu
SUMMARY:Graduate School Open House
DESCRIPTION:Join us at the Graduate School’s In-Person Open House event to learn more about Biological Sciences! The Graduate School will also pay the application fee for all applicants who attend the Open House (fee waiver eligibility requirements outlined here). \nClick here for more details and to register. 
URL:/biology/event/graduate-school-open-house-4/
LOCATION:Union Wisconsin Room East\, 2200 East 51����\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Department
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DTSTART;TZID=America/Chicago:20241108T160000
DTEND;TZID=America/Chicago:20241108T170000
DTSTAMP:20260419T223725
CREATED:20241105T194601Z
LAST-MODIFIED:20241105T194735Z
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SUMMARY:Biological Sciences Colloquium: Dr. Eillen Tecle
DESCRIPTION:Dr. Eillen Tecle\, Assistant Professor in the Department of Microbiology and Immunology at the Medical College of Wisconsin\, will present a talk about her work entitled\, “Purine nucleotide salvage enzymes regulate epithelial cell resistance to infection in C. elegans.”\n\n\nThe abstract is as follows:\n\n\n“The Intracellular Pathogen Response (IPR) was identified as a common host transcriptional response to diverse natural intracellular pathogens in C. elegans\, including the Orsay virus\, as well as Microsporidia\, which cause the most observed infection in wild-caught C. elegans. IPR genes in C. elegans are distinct from those induced by heat shock and other stressors. Constitutive IPR activation protects C. elegans from intracellular pathogen infection while compromising development and lifespan. Despite its dramatic effects on host physiology\, we know little about how the IPR is activated\, regulated\, and promotes defense. However\, we have identified a novel role for the C. elegans orthologs of human purine metabolism genes as negative regulators of the IPR. We are currently working to understand the mechanism by which these enzymes and\, more broadly\, purine metabolism regulate immunity.”\n\n\nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:/biology/event/biological-sciences-colloquium-dr-eillen-tecle/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:/biology/wp-content/uploads/sites/21/2024/11/2024-Nov-08-Tecle.jpg
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241115T160000
DTEND;TZID=America/Chicago:20241115T170000
DTSTAMP:20260419T223725
CREATED:20241112T210203Z
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SUMMARY:Biological Sciences Colloquium: Dr. Chris Quinn
DESCRIPTION:Dr. Chris Quinn of UW-Milwaukee will present a talk about his work entitled\, “Harnessing human genetics to investigate the development and degeneration of axons in C. elegans.” \nThe abstract is as follows: \n“Genome sequencing studies have generated a list of de novo variants that are associated with neurodevelopmental disorders such as autism and intellectual disability. However\, little is known about how variants in these genes can disrupt neuronal cell biology to cause defects in neurodevelopment. Our laboratory is using these variants to uncover novel mechanisms that regulate neuronal development in C. elegans. In the first part of this talk\, I will focus on our work with the RBM-26(RBM26/27) RNA binding protein. We found that mutations in rbm-26 cause mitochondrial dysfunction\, axon degeneration and axon targeting defects. Mechanistically\, we discovered that RBM-26 negatively regulates the MALS-1 mitoribosomal assembly factor and that this interaction is required to protect against axon degeneration and axon targeting defects. In the second part\, I will talk about the anc-1 ortholog of SYNE1\, which has been associated with autism and bipolar disorder. We have found that mutations in anc-1 disrupt the polarization of axon growth by disrupting the localization of mitochondria within the neuron. These studies highlight the roles that autism-associated genes can play in promoting mitochondrial function and how disruptions in these processes can lead to the defects in neurodevelopment that underlie autism.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:/biology/event/biological-sciences-colloquium-dr-chris-quinn/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:/biology/wp-content/uploads/sites/21/2024/11/2024-Nov-15-Quinn.jpg
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DTSTART;TZID=America/Chicago:20241122T160000
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CREATED:20241119T195109Z
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UID:10001362-1732291200-1732294800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Claudia Rodriguez
DESCRIPTION:Claudia Rodriguez\, graduate student of Biological Sciences at UW-Milwaukee\, will present a talk about her work entitled\, “An alternative mode of signal transduction by the EGL-15 FGF receptor in Caenorhabditis elegans.” \nThe abstract is as follows: \n“How is an animal body built and maintained? The answers lie in animal development\, which is regulated by cell signaling modules present in every animal\, from worms to mammals. One of these modules involves Fibroblast Growth Factors (FGFs) and their receptors (FGFRs)\, which stimulate Ras and the downstream kinases Raf\, MEK\, and ERK.  The Caenorhabditis elegans FGFR\, termed EGL-15\, is required in the sex myoblasts (SMs) for their cell migration during post-embryonic development\, and in the hypodermis (Hyp7) for homeostatic fluid balance throughout life. To investigate cell-specific differences between the SMs and Hyp7\, we used the kinase reporter ERK-KTR to assess activation of ERK. We found that EGL-15 utilized different signaling mechanisms in the SMs and Hyp7 and identified the IRS/DOK-like protein SOC-3 as required for EGL-15 signaling in Hyp7. This work highlights how one receptor can use cell-specific signaling mechanisms to achieve diverse developmental outcomes.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:/biology/event/biological-sciences-colloquium-claudia-rodriguez/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:/biology/wp-content/uploads/sites/21/2024/11/2024-Nov-22-Rodriguez.jpg
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